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Studies employing human GBM cell lines, animal models, or clinical data were considered, particularly those addressing critical pathways such as the bloodbrain barrier (BBB), glioblastoma stem cells (GSCs), and drug resistance

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Glutathione infusion therapy delivers glutathione directly into the bloodstream through intravenous (IV) administration for enhanced absorption and bioavailability

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doi:10.1089/ars.2013.5483 Alegre-Cebollada J, Kosuri P, Giganti D, Eckels E, Rivas-Pardo JA, Hamdani N, Warren CM, Solaro RJ, Linke WA, Fernandez JM (2014) S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding

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