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Nat Metab 2:12321247 [DOI] [PMC free article] [PubMed] [Google Scholar] Meiser J, Krmer L, Sapcariu SC, Battello N, Ghelfi J, DHerouel AF, Skupin A, Hiller K (2016) Pro-inflammatory macrophages sustain pyruvate oxidation through pyruvate dehydrogenase for the synthesis of itaconate and to enable cytokine expression

Trxs are also involved in iron homeostasis via regulation of IRP1 activity, as shown above [13]

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