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TABLE 2 Traditional Chinese medicine targeting ferroptosis in the treatment of AS

Arbutin is actually a compound of hydroquinone and D-glucose

Advanced management of local anesthetic systemic toxicity

Avoid spraying directly onto the lyophilized powder

In neuronal models exposed to 6-hydroxydopamine (6-OHDA), high ROS impairs mitophagy and exacerbates apoptosis ( Taken together, these data support a doseresponse paradigm: moderate ROS promote neuroprotection by activating AMPKmTORC1 and JNK signaling to facilitate PINK1/Parkin-mediated mitophagy, whereas chronic/excess ROS oxidatively disable ATG3/ATG7 and LAMP2, disrupt autophagic flux, drive accumulation of dysfunctional mitochondria, and accelerate neurodegeneration