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The entire organ is composed of cells of surface ectodermal origin at various stages of differentiation surrounded by a basal lamina, the lens capsule (Duncan 1981

In non-small cell lung cancer, NRF2 upregulates the expression of PHGDH, PSAT1 and SHMT2 by activating ATF4, thereby driving SSP activation, which is associated with poor clinical prognosis (101)