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3 Magnesium and Sleep Magnesiums relationship with sleep has been a growing area of research, and there are a few reasons why: 6 Magnesium helps regulate GABA, a neurotransmitter that calms neural activity and promotes relaxation, making it easier for the brain to wind down at the end of the day

Lipophilicity with Purpose: These molecules walk a tightrope between being hydrophobic enough to cross membranes but not so greasy that they precipitate or bind non-specifically to proteins

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Peak blood levels for the individual components occur 1 to 4 hours after oral administration