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This pathway may lead to increases in mitochondrial fatty acids beta-oxidation and reduction in the synthesis of TG and very-low-density lipoprotein (VLDL) cholesterol.[] Also, it was shown that increasing carnitine may have positive effects on body fat reduction and increment of oxidation of the fatty acids.[] Moreover, it has been suggested that the beneficial effects of improving vascular reactivity and antioxidant activity, which can be observed during the treatment with L-carnitine, may be due to decreased plasma lipid levels

it may ameliorate insulin resistance, inflammation, and protein wasting. Despite the body of evidence to support its use the authors somehow conclude LC administration continues to appeal to nephrologists because its use in dialysis patients has an attractive rationale, it addresses problems that persist despite dialysis, it is safe, and the existing literature does not refute its use

& Yu, A.-M

It may be also one of the symptoms of a more generalized disease

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