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TMAO impairs mitochondrial function, increasing ROS production, triggering the assembly and activation of the NLRP3 inflammasome [75, 144]

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Statin treatment caused a reduction in hepatic levels of several fatty acid species exclusively in females

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A standard curve was created using serial dilutions of plasmid DNA containing the target mtDNA sequence, and amplification efficiency was validated with a correlation coefficient above 0.98

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The typical form of seizures occurs within the first month of life, while in atypical patients, seizures may be delayed until infancy to 3 years of age

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