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However, it is not the only target

We demonstrated that exposure of microglia to the chosen cART cocktail induced generation of reactive oxygen species, subsequently leading to lysosomal dysfunction and dysregulated autophagy, ultimately resulting in the activation of microglia

[DOI] [PubMed] [Google Scholar] 38.Maiorino M., Aumann K.D., Brigelius-Floh R., Doria D., van den Heuvel J., McCarthy J., Roveri A., Ursini F., Floh L