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DAMP-driven innate immune activation and TLR signaling Tubular cell necrosis and apoptosis following I/R injury lead to the release of damage-associated molecular patterns (DAMPs), including HMGB1, mitochondrial DNA, and extracellular ATP

These include protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation

To tackle intracellular S

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Using Non-Sterile Techniques Maintaining sterility is essential to prevent contamination and infection