By binding to its receptor, VEGF induces VEGF receptor phosphorylation and activates mitogen-activated protein kinase (MAPK), which induces vascular endothelial cell proliferation (203, 204)
Acknowledgements The authors acknowledge support from the National Natural Science Foundation of China (grant numbers 42206208, 42261134536, 42076208), the International Partnership Program of the Chinese Academy of Sciences (grant no
This pathway is of great interest since it is associated with asthma, anaphylactic shock, and cardiovascular disease
An original clinical translational study linking overexpression of the NER DNA-repair pathway gene ERCC1 to poor response to platinum-based chemotherapy in patients with ovarian cancer
This process promotes neocollagenesis and collagen remodeling, enhances microcirculation, and supports lymphatic drainage.35 In addition to improving skin elasticity and the appearance of cellulite, acoustic waves may also help reduce localized adiposities through mechanical disruption and improved tissue structure.34 A meta-analysis conducted by Knobloch and Kraemer (2015) evaluated 11 clinical studies including 5 randomized controlled trials involving a total of 297 female patients with cellulite and demonstrated that both radial and focused extracorporeal SWT significantly reduced cellulite severity