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doi: 10.1080/16506073.2015.1098724

The sperm DNA damage was evaluated using various tests such as Comet assay, sperm chromatin structure assay, terminal deoxyuridine nick end labeling assay, and sperm chromatin dispersion assay.[] Therefore, despite that studies demonstrated correlation between sperm DNA damage and adverse ART events, the evidence is inconclusive as there is no standardization of the tests that has been used to detect sperm DNA damage

On the other hand, MAOA inhibition and TAAR1 activation by LDX (both direct targets of LDX) might influence MAPK3 activation, which is crucial for the downstream modulation of a large number of proteins involved in many biological processes, such as neuroinflammation [200]