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Description

CFD syndrome is defined as any neurological syndrome associated with low concentrations of 5-methyltetrahydrofolate in cerebrospinal fluid, while folate levels in plasma and red blood cells are within normal range

10.1006/meth.2001.1262 36 MahmoudS

Typically, before a drug can be marketed, it must pass through a series of clinical trials, in order to identify safe dosages and to determine that any positive outcomes are due to the substance itself, and not to bias in the study design