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Meanwhile, DNA methylation also regulates mitochondrial metabolic genes, such as carnitine palmitoyl transferase 1 A and acetyl-CoA carboxylase alpha, which are involved in lipid oxidation [43]

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In triple-negative breast cancer (TNBC), studies have demonstrated that tumor cells competitively prey on glutamine in the TME, resulting in the limited availability of glutamine for tumor-infiltrating T lymphocytes, which affects their anti-tumor immune responses

(1) Both these findings on chronic and acute action of AOD 9604 suggested that while enhanced beta(3)-AR expression may have played a role in the chronic action of the compound, beta(3)-AR might not be the sole arbiter in this reaction

[PMC free article] [PubMed] [Google Scholar] 117.Strazzullo P., Leclercq C