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Further investigation allowed to identify that the peripheral blood memory B cell population was altered in sarcoidosis patients compared to healthy subjects due to the decreased levels of unswitched (IgD + CD27+) and class-switched (IgD CD27+) memory B cells, whereas the levels of CD19 + CD24+++CD38+++ and CD19 + CD5 + CD27 regulatory B cells were increased (42)

Non-Small Cell Lung Cancer Lung cancer is the predominant cause of cancer-related mortality globally

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Nowadays, ROS production has also been observed in a variety of cells other than phagocytes, and their implication in physiologic signaling is well documented (Di Meo et al., 2016)