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From a genetic background perspective, TP53 mutation status significantly affects ferroptosis sensitivity by regulating the TP63/GPX4 axis, whereas CDKN2A deletion increases ferroptosis susceptibility by altering the lipid compartment distribution of PUFAs ( The spatiotemporal heterogeneity of the TIME further increases treatment complexity

Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets

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Taken together, monocytes from patients with SLE exhibit elevated expression of TCN2, which is associated with disease activity and involvement of the skin, kidneys, and joints

The transmitted electrical signals are sensitive to DNA modifications (which can deviate the raw signal), which is why this laboratory technique can be used for differentiating methylated from unmethylated cytosine residues in the DNA molecule [24]