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Though correlation with in vivo performance is difficult to establish (due to the availability and variability of published data) the drug release profile is consistent with reports of maximal therapeutic activity about five to six hours after injection

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Corneal repair, tendon biology, skeletal muscle repair, and neurological injury models have each been examined , collectively establishing TB-500 as a broad-spectrum repair peptide with particular depth of characterisation in cardiac and wound healing biology

However, REGEN does not prevent future injuries, so users returning to activities that caused the original injury risk re-injury if underlying biomechanics or training errors are not addressed