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Clinical Safety Data Human safety data for BPC-157 remains limited compared to the extensive preclinical toxicology database

Commentary on "Bortezomib, thalidomide, and dexamethasone for relapsed multiple myeloma: add it up and wait"

The evidence from vertebrate models and the discovery of an antioxidant response element (ARE) in the coral glutathione reductase gene putative promoter region suggest that BI-1 likely impacts coral antioxidant system through the Nrf2/ARE signaling pathway

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Yet, in contrast to eed1 , efg1 / cph1 mutants are avirulent during systemic and catheter infection models, suggesting that some degree of morphology changes as in eed1 , or genes under control of efg1 / cph1 are required in vivo 7,48