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Clec9a, a c-type lectin receptor on DCs responsible for capturing antigen and initiating subsequent cross-presentation, is expressed on human BDCA3 + (CD141) DCs and mouse CD8 + DCs [226]

Collagen electrophoresis can be used to study the effect of the variant but the absence of demonstration of abnormal collagen III produced by fibroblasts does not exclude the diagnosis

Thus, it is still unknown whether there is an underlying deficit in mitochondrial respiratory function in these HepG2 citrindeficient cells, or whether the observed phenotype is merely a result of reduced cell number and mitochondrial density related to the citrin deficiency

Szczepaska A, Olek K, Koodziejska K, Yu J, Ibrahim AT, Adamkiewicz L, Schroeder FC, Pokrzywa W, Turek M

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