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Through the Bellberry/ASCEPT NAMs Workshop Series, begun in Melbourne in November 2024, the private-sector HREC Bellberry is building committee competency to evaluate organ-on-chip and other NAM-derived evidence, with the TGA's Director of Toxicology participating in the working group (Mann et al., 2026)

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In addition to the liver and lung issues mentioned, there is also a link between the A1AT PI Z variant and antineutrophil cytoplasmatic antibody (ANCA)- associated vasculitis