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10.3389/fendo.2020.00025 401 SinghV.RothS.LloveraG.SadlerR.GarzettiD.StecherB.et al

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The results showed that fluorescence signals from all three suppository formulations were primarily detected within the colorectum over time, with only weak signals observed in major organs, including the heart, liver, spleen, lungs, kidneys, and small intestine