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After taking the medicine for 57 days in mild cases and 12 months in severe cases, patients clinical symptoms were basically relieved, and X-ray films showed that the bone changes were basically corrected or in a stable state

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There are also patient-selection questions that fall outside the scope of an educational page but are central to responsible practice: GH-axis stimulation is not appropriate for everyone, and active or suspected malignancy is one of several contexts where stimulating growth signaling raises clear concern

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ACKNOWLEDGEMENTS This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2011-0008199).