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In this regard, it has been shown that tamoxifen, a type of selective estrogen receptor modulator (SERM) that acts as a competitive antagonist or as a partial agonist depending on the cell type, favors the repair of demyelinated lesions in the CNS by increasing the mRNA levels of myelin basic protein (MBP) and 2, 3-Cyclic nucleotide 3-phosphodiesterase (CNP), two genes highly expressed during oligodendroglial differentiation (Gonzalez et al., 2016)

DAA and reactive astrocytes in AD Alongside microglia, astrocyte heterogeneity plays a crucial role in AD pathogenesis (Figure 3)

Aqua, Butylene Glycol, Glycerin, Copper Tripeptide-1, Acetyl Tetrapeptide-3, Trifolium Pratense Flower Extract, Arginine, Panthenol, Niacinamide, Sodium Hyaluronate, Allantoin, 1,2-Hexanediol, p-Hydroxyacetophenone, Xanthan Gum, Disodium EDTA

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Targets Peptide API with hydrophilic properties and low oral bioavailability, requiring stabilization strategies for oral dosage forms