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SKU: 81676987178
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Description

Under homeostatic conditions, Nrf2 is repressed by its tight association with the Kelch-like ECH-associated protein 1 (Keap1), which promotes Nrf2 ubiquitination and degradation through the ubiquitin-proteasome pathway

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Here, we comprehensively review studies regarding dysregulated cell signaling, especially in ATII cells, and their contribution to alveolar wall destruction in emphysema