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At the same time, it can effectively raise healthy appetite, allowing users to ingest more high-quality protein and surplus calories, thus supplying abundant essential nutrients for sustained muscle growth

However, their increasing use raises concerns about cytotoxic effects on human health and the environment

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Oxidative stress damage is further compounded in patients requiring dialysis therapy due to the bio-incompatibility of dialysis membranes in HD or solutions in PD [22, 23]