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Glutathionyl transferase catalyzed addition of glutathione to Comc: a new hypothesis for antitumor activity

doi: 10.1016/j.canlet.2021.09.014 256 ZhaoNHuangYWangYHMuirRKChenYCWeiJet al

Under oxidative stress conditions, activation of the immune system commonly has a short life because of intrinsic negative feedback mechanisms such as enhanced generation of the antioxidant cascade system and anti-inflammatory cytokines

However, vitamin B12 can be stored in the liver for a long time, so it does not easily become deficient

Glutathione (GSH) acts as a redox buffer, serving as a reducing agent, playing a role in toxin removal, and protecting against oxidative stress