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Quite remarkably, in those with low POP levels, the typically robust association between diabetes and obesity was not observed in a nested case-controlled study, suggesting that obesity may exaggerate the metabolic disturbances caused by POPs (perhaps because adipose tissue provides a reservoir for fat-soluble toxins), rather than being directly responsible for the altered metabolism

(3) Abedi P, Zohrabi I, Ansari S, Maraghi E, et al

This has drawn interest from researchers studying shift workers and those with circadian misalignment

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Ikemoto, 2003), and hypothalamus (feeding and reward) (Nakajima and McKenzie, 1986