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doi:10.1016/j.ajhg.2016.03.005

Mood changes : Low B12 can also cause symptoms such as depression, irritability, and mood changes

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Acknowledgments We thank the UK Biobank study, and the summary statistics data of UKB can be download from Neale lab ( and other GWAS summary-level data, which have been downloaded from We also thank all the reviewers and editors for their useful suggestions for improving this study