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Arginine is also a precursor to nitric oxide

The synergy between exogenous MOTS-c and exercise is not merely additive: because MOTS-c mimics one of the molecular consequences of high-intensity exercise (AMPK activation via AICAR accumulation), concurrent exercise training may amplify the peptide's effects on GLUT4 translocation and mitochondrial biogenesis

In a study of 10 individuals unresponsive to conventional rectal therapies and oral aminosalicylates, nightly butyrate enemas (60 mL, 80 mM) resulted in a complete response in 40% of cases and an overall response in 60% of cases [143]

R., Ritchie, S., Pereira, B

Moschos MM, Dettoraki M, Tsatsos M, Kitsos G, Kalogeropoulos C