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Clinical studies indicate that postmenopausal women exhibit a ~30% reduction in ATP production efficiency, which associates directly with decreased activity of mitochondrial complex IV, COX (118)

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The counteracting cellular antioxidant systems include both enzymatic, such as catalase, superoxide dismutase (SOD), glutathione peroxidase, and nonenzymatic, such as glutathione (GSH), vitamin C, vitamin E, members (Haida and Hakiman 2019)

Report suspected adverse reactions to the FDA MedWatch Program at 1-800-FDA-1088 or online at www.fda.gov/medwatch