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Patients with active inflammatory bowel disease, especially those with ongoing flares, may find tirzepatide GI effects intolerable or confusing from a symptom monitoring perspective

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J Nutr 137(12):26472652 Lamers Y, Williamson J, Ralat M, Quinlivan EP, Gilbert LR, Keeling C, Stevens RD, Newgard CB, Ueland PM, Meyer K, Fredriksen A, Stacpoole PW, Gregory JF 3rd (2009) Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and women

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