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then superoxide anions can react with reducing substances or biological macromolecules, for example superoxide dismutase (SOD) to produce H 2 O 2 [21]

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The latter possibility is consistent with the report that KLF9 acts as a transcriptional mediator of glucocorticoid-regulated, KLF9 family member KLF2 in macrophages to promote inflammation (Chinenov et al., 2014)

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