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Toxic A oligomers activate microglia and encourage the release of pro-inflammatory cytokines (De Felice et al., 2022)

Zussman et al

P.GeorgievM

This step commits acetyl-CoA to fatty acid synthesis for two reasons: (i) its product, malonyl-CoA, prevents the oxidation of fatty acids to mitochondria by inhibiting their entry at the level of carnitine palmitoyltransferase 1 (Fig