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While its traditional use and numerous clinical studies indicate relative safety at typical therapeutic doses [228], emerging data call for a more nuanced evaluation of potential risks

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doi: 10.1038/s41586-022-05022-3 87 NioiPHayesJD

In recent years, there has been a growing scholarly interest in the PNS attributable to its multiple physiological and pathophysiological non-sensory roles in the organs it innervates