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The lyophilized format gives researchers complete control over their concentration and protocol

In the rat, they represent only approximately 10% of the total number of OR, while in most other species (guinea pig, monkey, and human) they represent at least a third of the opioid binding population (Dhawan et al., 2012

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10.1038/s41418-017-0012-4 64 GaoM.MonianP.QuadriN.RamasamyR.JiangX

Despite a limited amount of data, it is reasonable to postulate that dysregulated control of macrophage survival in an inflamed environment could exaggerate inflammation, and this could be relevant to the initiation or progression of CD