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Author Contributions HT, APM and JJW conceptualized the studies, HT, APM, AJP and RCG performed the experiments, HT and JJW wrote the original draft of the manuscript, APM, AJP and RCG edited and reviewed the manuscript, and JJW, HT, AJP and APM acquired funding

This study protocol was approved by the Institutional Review Board of the First Affiliated Hospital of Chengdu Medical College (approval No

Moreover, GABA had no significant effect on GOGAT under controlled and SS conditions ( Figures 6BD )

In contrast, foregoing study has reported that inhibition of p38 MAPK pathway resulted in upregulation of reactive oxygen species, mediating activation of JNK and thereby sensitizing human tumor cells to cisplatin induced apoptosis [82]

How Vitamin B12 helps the body Vitamin B12 Deficiency Vitamin B12 deficiency occurs when the body lacks an adequate amount of vitamin B12 to maintain optimal health and functioning