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The major adverse effects of topical retinoids and topical vitamin C are local skin irritation, including erythema, peeling, dryness, burning and itching, which depend on the concentration and formulation of the product (129,130)

The intersection of the pharmaceutical-target disease genes was obtained using by jvenn

doi: 10.3389/fphys.2021.676782 23 FalfushynskaHISokolovEPiontkivskaHSokolovaIM

Br J Nutr 127(3):398402 Ligthart-Melis GC, vande Poll MC, Boelens PG, Dejong CH, Deutz NE, van Leeuwen PA (2008) Glutamine is an importantprecursor for de novo synthesis of arginine in humans

Independently, Chromcova and colleagues (2013[7]) and Nwani and colleagues (2010[34]) have also reported an increase in LOOH level due to the Atrazine exposure of various fish species