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[205] [198] [76] Phosphorylation of DAT by either kinase induces transporter internalization (non-competitive reuptake inhibition), but PKC-mediated phosphorylation alone induces the reversal of dopamine transport through DAT (i.e., dopamine efflux)

Questo elemento centrale per comprendere perch qualsiasi discussione sul dosaggio rimanga, ad oggi, nell'ambito della ricerca e dell'esperienza aneddotica

Pfeffer PE, Lu H, Mann EH, Chen Y-H, Ho T-R, Cousins DJ, et al

First, all the rats were anesthetized via an intraperitoneal injection of 2% pentobarbital sodium (75 mg/kg), and the hair of the right posterior leg was removed