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spina bifida)

The dual role of zinc on aggregation and fibrillation of -synuclein has been summarised in Figure 3

In support of this, a recent study has shown that Nrf2, the master regulator of antioxidant response plays a role in mitohormesis (induced by a small degree of mitochondrial uncoupling) in skeletal muscle of transgenic mice deficient in oxidative phosphorylation capacity (25)