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10.1038/nature10350 39 PournasrB.DuncanS

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Linuron is a well-characterized anti-androgenic herbicide that can antagonize the AR in vitro , but also inhibit the synthesis of androgens such as testosterone and androstenedione ( in vivo studies show decreased testosterone levels indicating that this compound could also affect steroidogenesis in vivo

A study investigating the effect of folate and cobalamin deficiency during pregnancy found that deficiencies of these vitamins cause recurrent spontaneous abortion, preterm delivery, fetal malformations, low birth weight, stillbirth, and abruption of the placenta