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A comparative review noted that the specific polymorphisms that might, in theory, favor one form are generally not reported in commercial genetic tests, and no randomized trial has validated genotype-guided form selection in healthy people

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It is sold under research-use-only labeling and is not regulated as a dietary supplement either

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This is especially true when the vitamin status is poor during the pregnancy and if the early-introduced foods fed to the still-breastfeeding infant are vegan