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258 Its inhibition of 3T3-L1 adipocyte differentiation is an indirect function, involving the suppression of PPAR transcriptional activity and a decrease in reactive oxygen species (ROS) levels during early adipogenesis

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In respiratory disease, cellular damage and injury is mediated by an increased oxidant burden and/or decreased antioxidant defenses

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On one hand, STING activation has been shown to promote the differentiation of nave CD4 T cells into Th1 and Th9 cells and enhance the production of effector cytokines such as IFN- and IL-9, thereby augmenting CD4 T cell effector functions [229]