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Extreme temperatures, both hot and cold, can affect the stability of the benzyl alcohol

30 , 31 Several preclinical studies have investigated the effect of high doses of vitamin C on challenging tumours such as glioblastoma multiform (GBM), breast cancer, colorectal cancer, mesothelioma and pancreatic cancer and showed promising results on the anticancer effect of vitamin C through hampering the tumour progression and tumour metastasis

There are three classical signal transduction pathways involved in the development of endoplasmic reticulum stress: IRE1, PERK, and ATF6

The antioxidant activity of the resveratrol is exerted by its capacity to neutralize free radicals but also from its ability inactivating the antioxidant enzymes such as SOD, CAT, and GPx (Izzo et al., 2021)

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