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In preclinical studies, researchers constructed Arginine-Glycine-Aspartic acid-Human Serum Albumin-Tacrolimus (RGD-HSA-TAC) nanoparticles to target the delivery of tacrolimus to podocytes, which resulted in a reduction of podocyte injury and albuminuria in mice with diabetic kidney disease (148)

Together, they are often compared in preclinical study designs focused on wound model behaviour, tendon matrix research, vascular signalling, and coordinated cellular repair mechanisms

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