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Bisphenol S exposure modulate macrophage phenotype as defined by cytokines profiling, global metabolomics and lipidomics analysis

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Clinically low plasma and intracellular Gln concentrations and decreased mucosal glutaminase activity in Crohns disease patients indicated that Gln metabolism was impaired therein, from which it was hypothesized that Gln supplementation would improve the clinical manifestations of Crohns disease (24)

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