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Mild Discomfort: Some individuals experience redness or swelling at the injection site

Lyophilization removes water from the peptide under low temperature and vacuum conditions, transforming it into a stable powder

In orthotopic osteosarcoma models lacking fusions, pharmacologic TrkA blockade dampened NGF-induced MMP-2 programs and reduced metastatic spread, consistent with the NGF/MMP axis observed in patient and cell-based datasets (90, 91)