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Description

10.1002/jor.24529 J

Although GWAS is effective at detecting common variants with small effect sizes, it is less suited for identifying rare variants, which often have larger effects but require much larger sample sizes and specialized statistical approaches [27,28,29]

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Research context What is in this stack

Figure 2 provides an integrated schematic overview of vitamin D metabolism and its genomic and non-genomic signaling pathways across metabolic and ovarian tissues, summarizing the mechanisms described in this section