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This in turn permits to increase the diffusion of Pt ions and reverts platinum drug resistance 93

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Oxidative stress can cause insulin resistance and episodes of hypoglycemia

At weeks 12, the Warburg effect, pentose phosphate pathway, glycine and serine, glutathione, glutamate, methionine, alanine, phenylalanine and tyrosine, arginine and proline, taurine and hypotaurine, and aspartate metabolisms, ammonia recycling, urea cycle, glycerol phosphate shuttle, gluconeogenesis, glucose-alanine cycle and glycolysis pathways were significantly altered in ALS compared to control cells (Fig