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Xu, Y., Liu, W

M., Choquette, A., Talantsev, E

Improved blood sugar control and weight loss in T2D: A 32-week phase 2 trial, involving 92 participants with T2D, revealed that weekly doses of 2.4 mg cagrilintide + semaglutide reduced HbA1c levels by -2.2%, fasting blood sugar by -3.3 mmol/L, and body weight by -15.6% from baseline [12]

It is characterized by microglial activation and enhanced release of inflammatory factors, such as tumor necrosis factor (TNF-), IL-2, IL-10, IL-4, IL-6, and interferon , which contribute to neuronal injury and death [30, 31]