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10~25mg of Thioctic acid injection per day

Usually, theres some discomfort, but with a local anaesthetic, most people tolerate it well

Real time Quantitative PCR Method RNA was extracted using the RNeasy Mini kit (QIAGEN, 74106)

Injections tend to hurt most when the cortisone is delivered to a small space

To examine whether the administration of the Si-based agent alleviates the visceral pain and discomfort associated with UC, we investigated the neuronal activities in the nuclei of the dorsal medulla oblongata [the nuclei of the solitary tract (NST) and the dorsal vagal nuclei (DVN)], and the central amygdala (CeA) using immunostaining for c-Fos, a neuronal active marker