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Heliyon 7 , e07805 (2021)

Mitochondrial dysfunction enhances ROS generation via the NADPH oxidase pathway (135)

Role of metabolism in ocular drug delivery

7 However, recently several studies reported a protective role of ROS in immune-mediated inflammatory disease, because an imbalance between ROS generation and scavenging may contribute to abnormal T-cell responses

The intestinal barrier may, therefore, be a target for therapeutic approaches to alter the course and mitigate the complications associated with a disruption in its functions